Sulbutiamine is a highly efficient Vitamin B1 derivative used primarily to fight asthenia – lack of strength or energy. Sulbutiamine (more commonly known as Arcalion) is the only anti-asthenic compound known to cross the blood-brain barrier and to be selectively active on specific brain structures directly involved in asthenia. Sulbutiamine could perhaps be seen as stronger version of the hugely popular nootropic drug Hydergine.

Sulbutiamine reduces fatigue, memory difficulties, intellectual tiredness and may speed convalescence. Because of its fatigue fighting capabilities Sulbutiamine is often used by those who are involved in physically demanding situations. Perhaps more in keeping with other nootropic drugs, Sulbutiamine also promotes alertness, strengthens long-term memory, improves reaction time, lowers anxiety, and improves resistance to stress