Picamilon - (100 mg x 60 capsules)

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Quick Overview

Picamilon (also known as N-nicotinoyl-GABA, Pycamilon and Pikamilon) is a nootropic created in 1969 used for cognitive support.

• Anxiety & Stress Relief

• Learning & Memory Enhancement

• Improved Concentration, Alertness & Mental Stamina

• Brain & Body Relaxation Without Sedation

• Improves Sleep

It provides a tranquilized yet energized state of being.

Suggested Use: As a dietary supplement, take 1 or 2 capsules daily or as recommended by your health care professional.

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What is Picamilon?

Picamilon is the chemical bonding of two nutrients GABA (gamma-amino-butyric acid) and Niacin (Nicotinic acid) and it was synthesized in 1969 by the All-Union Scientific Research Institute. The bonding of these two nutrients into one compound has created unique spectrums of beneficial nootropic (cognitive enhancing) effects. The preparation was introduced in medical practice over 25 years ago.


Picamilon Uses

Interest in Picamilon may be attributed to the unique combination of its pharmacological properties. It possesses high cerebrovascular activity and nootropic effects but also a unique tranquilizing effect without myorelaxation effect. Picamilon has the ability to quickly restore mental and physical fitness for work, often lost through overstress. Studies have shown that Picamilon dramatically increases blood flow and circulation within the brain, and achieves results far superior to other nootropic agents. Picamilon's tranquilizing action prevents the negative physiological effects of emotional stress, it helps moderate states of anxiety and depressed negative emotions but Picamilon doesn't have any sedative qualities. Uniquely Picamilon provides a tranquilized yet energized state of being.

Picamilon is used in the capacity of a nootropic and vasoactive agent for mild to moderate ischemic disturbances of the cerebral blood circulation. It is also used for discirculatory encephalopathy, vegetative dystonia, craniocerebral traumas, neuroinfections and migraine. Picamilon has proven to be an effective medicinal treatment for patients with disorders of a neurotic level, with accompanying manifestations of anxiety, elevated irritability fear, emotional and vegetative instability. Additionally, within the elderly Picamilone assists with senile psychosis and depressive disorders and it is used in the treatment of alcoholism and acute alcoholic intoxication.

More recently Picamilone has been used in opthalmological practice for diseases of the retina and the optic nerve and for primary open-angle glaucoma. It has also shown some value with urological disorders in children and adults in improving the function of the urinary bladder.

Consult with your medical professional before taking.

Picamilon Effects

Picamilon's effects are usually felt within an hour and lasts between 4-6 hours. Picamilon provides a mild tranquilizing and mood stabilizing effect without sedation in small doses of 50mg three times per day. Higher doses of perhaps100mg three times per day will provide a stimulating influence increasing energy and endurance. Picamilon's cognitive enhancing effects are cumulative and become more evident after several weeks of daily usage.

As noted by many clinicians and physicians the varied therapeutic actions of Picamilon opens up its wider possibilities as a medicinal and preventive product especially if you consider Picamilon's low toxicity and lack of allergenic or carcinogenic properties and minimal side effects which include occasional headaches, dizziness and nausea.

Stacking with Other Nootropics

Picamilon may be synergistic with other nootropics so reduce overall dosages. Acquire a medical professional's advice should you be taking or plan to start taking Picamilon particularly if combining with potent vasodilators such as, ginkgo biloba, nicergoline, xanthinol nicotinate or vinpocetine. Avoid combining it with other MAO-A products like Deprenyl, GH3 or SSRI's like Prozac unless under the recommendation of your physician. Anyone taking any other prescribed medication or pregnant / lactating women should consult a physician before using Picamilon. If using long-term, supervision and monitoring by a health care professional is recommended.


  1. Gabaergic mechanism of cerebrovascular and neuroprotective effects of afobazole and picamilon. Read Full Article
  2. Preclinical prognosis of pyracetam and picamilon safety based on acute toxicity data. - Read Full Article
  3. Neurotrophic action of nicotinamide and nicotinoyl-GABA in rat brain in experimental Parkinsonism - Read Full Article
  4. Correction by nicotinamide and nicotinoyl-GABA of dopamine metabolism in rat brain in experimental Parkinson’s disease. - Read Full Article
  5. State of GABA-benzodiazepine receptor complex in diabetic neuropathy: effect of nicotinamide and nicotinoyl-GABA. - Read Full Article
  6. The effect of hypokinesia on depression and on the central GABA-A receptor complexes in the rat brain. - Read Full Article
  7. Evaluation of isonicotinoyl-gamma-aminobutyric acid (GABA) and nicotinoyl-GABA as pro-drugs of GABA. - Read Full Article
  8. Effect of nootropes on quantitative changes in the rat cerebral cortex GABA(A) receptor complexes under experimental hypokinesia conditions. - Read Full Article
  9. Oxidative stress correction by nicotinamide and nicotynol-GABA in diabetic neuropathy. - Read Full Article
  10. Pathogenetic treatment of central chorioretinal dystrophies with pikamilon. - Read Full Article
  11. Effects of aminalon, fenibut, and picamilon on the typological parameters of cerebral hemodynamics in swimmers with dysadaptation syndrome. - Read Full Article
  12. Effects of pikamilon on the brain water-electrolyte balance and in models of responses to the noise and vibration exposure, and their combination with motion sickness. - Read Full Article

Additional Information


Picamilon (100 mg x 60 capsules)

SKU Picamilon-001

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Customer Reviews

I really like Picamilon
I really like Picamilon and found it to be effective for helping me stay focused at work, with no side effects. Review by Amy, Texas

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